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  1. NARCAN® Nasal Spray

    Naloxone, the active ingredient in NARCAN® Nasal Spray, competes with opioids to bind with the same receptors in the brain, reversing the effects of an opioid overdose in 2 to 3 minutes.

  2. Narcan Nasal Spray: Opioid Overdose, Instructions and more

    Jul 11, 2024 · Narcan nasal spray (naloxone) is an over-the-counter medicine used to treat an opioid overdose emergency, Narcan works by rapidly reversing the opioid's effects.

  3. Naloxone - Wikipedia

    Naloxone, sold under the brand name Narcan among others, is an opioid antagonist, a medication used to reverse or reduce the effects of opioids. [14] For example, it is used to restore breathing after an …

  4. Narcan: Dosage, How It's Given, How It Works, Uses, and More

    Sep 28, 2023 · Narcan is used for emergency treatment of opioid overdose. It’s an opioid antagonist, which means it works by blocking certain receptors (attachment sites) in your body that opioids bind to.

  5. 5 Things to Know About Naloxone | Overdose Prevention | CDC

    May 2, 2024 · Naloxone, for example Narcan®, is a medicine that can help people who are overdosing on an opioid. Opioids include prescription medications, heroin, and fentanyl.

  6. How Narcan works: Mechanism of action explained - Medical News …

    Jul 3, 2025 · Narcan (naloxone) is an over-the-counter (OTC) medication that treats opioid overdose. Its mechanism of action is to quickly block opioids in your system.

  7. Naloxone DrugFacts | National Institute on Drug Abuse (NIDA)

    Jan 11, 2022 · Prepackaged Nasal Spray (generic naloxone, Narcan®, Kloxxado®), developed as a result of NIDA-funded research, is an FDA-approved prefilled, needle-free device that requires no …

  8. Naloxone (Narcan, Kloxxado, and others): Uses, Side Effects ... - WebMD

    Nov 1, 2024 · Find patient medical information for Naloxone (Narcan, Kloxxado, and others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings

  9. Opioid Overdose Reversal Medications - OORM | SAMHSA

    Aug 12, 2025 · Opioid overdose reversal medications (OORMs) are lifesaving medications approved by the Food and Drug Administration (FDA) to reverse an opioid overdose. Two FDA-approved OORMs …

  10. What is Narcan (naloxone)? Uses, how it works, and where to get it

    May 30, 2025 · Learn what Narcan (naloxone) is, how it reverses opioid overdoses, where to get it, and how to use it safely with support from QuickMD