The authors investigated the epigenetic mechanisms regulating the differentiation of circulating monocytes that infiltrate the CNS and adopt microglia-like characteristics. The work is useful to the ...
A new marker activate the ink flow #urday #macro #closeup Coach John Beam dies after being shot on college campus Barrett Deals Major Blow in Trump Case Omaha Steaks CEO warns American families will ...
Objectives Tumour necrosis factor inhibitors (TNFi) are widely used and effective as treatment for immune-mediated inflammatory diseases (IMIDs). However, TNFi therapy causes a faster waning of ...
The identification of reliable biomarkers from peripheral blood is crucial for improving disease diagnosis and monitoring. Spectral flow cytometry has emerged as a powerful tool for high-dimensional ...
A diagram illustrating the potential functions of ADA2 transported to endolysosomes of monocytes/macrophages and secreted externally from the cells. Adenosine deaminase 2 (ADA2) plays a critical role ...
Not all patients respond well to chimeric antigen receptor (CAR) T cell therapies, which reprogram a patient’s own immune cells to recognize and attack cancer. A way to optimize these treatments is to ...
Background: Trafficking of immune cells to the central nervous system is hypothesized to facilitate HIV entry and immune-induced neuronal injury and is mediated by surface proteins such as chemokine ...
Objectives The aim of this study was to combine deep T cell phenotyping with assessment of citrulline-reactive CD4+T cells in the pre-rheumatoid arthritis (RA) phase. Methods 20 anti-CCP2 positive ...
The Allen Institute for Immunology as a whole seeks to advance the fundamental understanding of the immune system by employing a full spectrum of -omics tools to understand the molecular pathways and ...
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