DUBAI, United Arab Emirates (AP) — Israel launched an expanded assault on Iran on Sunday, with direct strikes targeting its energy industry and Defense Ministry headquarters, while Tehran unleashed a fresh barrage of missiles blamed for the deaths of four people and injuries of many others.

The death toll from Iranian strikes on Israel continue to rise overnight as Israel and Iran exchange more missile and drone strikes. Israel’s national emergency service Magen David Adom (MDA) reported a “direct hit” on a residential building in the Palestinian-Israeli town of Tamra,

Iranian media reported that Israel struck the South Pars Gas Field in what would be the first attack on an Iranian energy site.

Russia has maintained a delicate balancing act in the Middle East for decades, trying to navigate its warm relations with Israel even as it has developed strong economic and military ties with Iran.

The Dow, S&P 500, and Nasdaq fell Friday as the stock market reacted to the escalating conflict between Israel and Iran.

Dow Jones Industrial Average (DJIA) futures is down 442 points, while S&P 500 (SPX) and Nasdaq-100 (NDX) futures are also deep in the red. Oil prices are soaring, with West Texas Intermediate (WTI) July-dated crude last seen 8.