The 49ers will wrap up a massively disappointing season without a number of starters when they face the Cardinals in Week 18.

The Arizona Cardinals will host the San Francisco 49ers at State Farm Stadium in Glendale, Arizona, on Sunday, January 5, at 1:25 p.m. PT. The Cardinals ...

San Francisco 49ers quarterback Brock Purdy exited Monday night's shootout with the Detroit Lions in the final two minutes, as the Niners were driving for a late touchdown to cut the Lions' lead to ...

The stage is set for the biggest regular season game in NFL history as the Detroit Lions take on the Minnesota Vikings on ...

The Seahawks hit the road for the final time this season as they get set to take on the division rival L.A. Rams in Week 18. Seahawks reporter Jen Mueller breaks down the Seahawks' final game of the ...

This year, Detroit surged to a 12-1 record to start the season and has been one of the top teams in the NFL for months. Both Lions' losses -- a 20-16 setback against Tampa Bay and a 48-42 defeat at ...

Nick Khan's prediction becomes a reality on Monday night. The World Wrestling Entertainment executive said during earning ...

Former Pittsburgh Steelers quarterback Josh Dobbs will start for the San Francisco 49ers in their game against the Arizona ...

San Francisco 49ers coach Kyle Shanahan initially was concerned about the elbow injury Brock Purdy sustained against the ...

Darnold signed a one-year deal worth $10 million to join the Vikings ahead of this season. Last week, Spotrac projected his ...

Gibbs has taken the workhorse role in the first two games without Montgomery and run with the opportunity. He has back-to-back games with 100-plus rushing yards, and has continued to be a receiving ...

Cardinals QB Kyler Murray is hoping for a strong performance heading into the offseason Sunday, while Joshua Dobbs starts for the 49ers with Brock Purdy out.