KEY TAKEAWAYS Flights continued to be cancelled in the U.S. on Wednesday, as the historic winter storm that hit Louisiana, Texas and other Gulf Coast states continued spreading for a second day.As many as 69% of departures out of New Orleans Wednesday have been cancelled,

With a winter storm moving through the southeastern U.S., even impacting Florida, weather conditions are having an effect on some flights into and out of Tampa International Airport.

Less than two weeks after Winter Storm Cora grounded flights throughout the Gulf Coast, Winter Storm Enzo has caused hundreds of flight cancellations and even more delays.

Storm Enzo sweeps across the Gulf Coast, it’s leaving a trail of travel disruptions in its wake. The rare winter weather has blanketed the region with snow and ice, causing widespread flight cancellations and treacherous road conditions.

Travelers have also been forced to wait for extended periods of time to pass through security and endure long waits for flights.

Storm Enzo has severely impacted airports across several states, leading to the closure of airports in Houston and Jacksonville.

Houston airports suspended operations and flights were largely scrubbed in New Orleans.

Thousands of flights at three airports were canceled amid a storm that caused "extremely hazardous" travel conditions in the Houston region.

Flight cancellations are mounting as a historic winter storm sweeps across the Gulf Coast. Already, the storm has brought air traffic to a virtual standstill at several airports across parts of Texas and Louisiana.