The San Francisco 49ers continue to take hits to their front seven, as defensive end Mykel Williams suffered an injury on Sunday.

The San Francisco 49ers (5-2) visit the Houston Texans (2-4) Sunday in Week 8. Kickoff from NRG Stadium in Houston, Texas, is ...

The NFL approved minority sales for the San Francisco 49ers, New York Giants and New England Patriots at the NFL league ...

Grant Cohn discusses how Clelin Ferrell and Keion White will change the San Francisco 49ers' defense.

San Francisco 49ers fans were treated to a concerning injury update regarding quarterback Brock Purdy during the Sunday Night Football broadcast of the team's game against the Falcons.

OPINION: Buster Posey didn't just think outside the box in hiring Tony Vitello to be the new manager of the San Francisco ...

Explore Mission Local's timeline of 100+ years at the Hunters Point Shipyard, San Francisco's only Superfund site.

Treasure Island is located between San Francisco and Oakland. It is often overlooked by people who pass through without stopping.

When it was announced earlier this year three NFL teams had been granted the marketing rights to promote American football in the UAE, Dustin Cherniawski said he had his fingers crossed who was going ...

Cameron Colvin, an ex-NFL player, has been indicted on federal charges of wire fraud and money laundering. The nine-page ...

We're staying on top of the latest happenings from across the Valley, state, and our nation for Friday, October 31.

Serie A and La Liga are so desperate to take their shows on the road, it appears they have not considered if there are any ...