This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

Since 1987, the Bulletin of the Atomic Scientists has published the Nuclear Notebook, an authoritative accounting of world nuclear arsenals compiled by top experts from the Federation of American ...

Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on knowledge of ...