A defining duo of the first Donald Trump administration is back.

Sen. Lisa Murkowski announced Thursday that she would vote against confirming Pete Hegseth to lead the Pentagon, becoming the first Republican to oppose one of President Donald Trump’s Cabinet picks. Maine GOP Sen. Susan Collins also voted against Hegseth.

The Senate advanced the nomination of Pete Hegseth as President Donald Trump's defense secretary Thursday on a largely party-line vote, despite grave objections from Democrats and stirring unease

GOP Sen. Lisa Murkowski says she "cannot in good conscience" support Pete Hegseth for secretary of defense, and she and Sen. Susan Collins voted "no" on his nomination in a procedural vote.

Two Republicans, Sen. Lisa Murkowski of Alaska and Sen. Susan Collins of Maine, broke ranks and voted against nominating Hegseth.

Donald Trump's pick for Defense Secretary, Pete Hegseth, is facing stiff criticism from Democrats—but most Republicans back him.

Sen. Susan Collins (R-Maine), one of two Republicans to vote against advancing Pete Hegseth’s nomination to serve as secretary of Defense, said Thursday he “does not have the management experience

Pete Hegseth has lost the support of two GOP senators ahead of a final confirmation vote.

Collins was one of two Republican senators to break ranks and oppose Hegseth Thursday, but it didn't stop the nomination from moving forward.

The Alaska Republican plans to vote against the confirmation of Pete Hegseth to lead the Department of Defense.

Senators voted 51-49 to advance Hegseth's defense secretary bid, which has been mired in a series of controversies. Two Republicans are opposed to Hegseth.