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This study identifies astrocyte-intrinsic mechanisms by which the LRRK2 G2019S, a mutation linked to familial Parkinson's disease, disrupts synaptic integrity in the anterior cingulate cortex. The ...
CRISPR construct to genetically ablate the GABA transporter GAT3 in the mouse visual cortex, with effects on population-level neuronal activity. This work is important, as it sheds light on how GAT3 ...
Hippocampal single-cell RNA Atlas of chronic methamphetamine abuse-induced cognitive decline in mice
The authors proposed two hypotheses: first, that methamphetamine induces neuroinflammation, and second, that it alters neuronal stem cell differentiation. These are valuable hypotheses, and the ...
This study offers important insights into the development of infants' responses to music based on the exploration of EEG neural auditory responses and video-based movement analysis. The convincing ...
High-throughput synapse profiling reveals cell-type-specific spatial configurations in the fly brain
Characterization of intracellular synapse heterogeneity aides to understand the intricate computational logic of neuronal circuits. Despite recent advances in connectomics, the spatial patterns of ...
The Drosophila microbiome regulates the cycling of gut metabolites in a circadian clock and diet-dependent manner.
Malaria merozoite surface proteins (MSPs), are thought to have important roles in red blood cell (RBC) invasion and their exposure on the parasite surface makes them attractive vaccine candidates.
Parasitic tapeworm larvae release glutamate and other excitatory molecules that can directly excite brain neurons.
Trained immunity in alveolar macrophages can lead to damaging lung inflammation, confirming the importance of context in this phenomenon.
Foveal sensitivity to the features of an imminent saccade target increases with the target’s conspicuity, supporting foveal prediction as a viable mechanism for maintaining visual continuity in ...
Insects possess a remarkable ability to develop innate immune memory, and the mechanisms underlying this process are becoming a central topic in innate immunity research.
Longitudinal tracking of neuronal activity from the same cells in the developing brain using Track2p
This important study presents a new method for longitudinally tracking cells in two-photon imaging data that addresses the specific challenges of imaging neurons in the developing cortex. It provides ...
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