When people who use illegal drugs feel like they have to hide their use, the risk of overdose and death soars.

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

The terms “addiction” and “dependence” can seem similar, but they are different. Dependence occurs when the body physically relies on a drug. Addiction involves changes in behavior. A person with an ...

The roots of addiction risk may lie in how young brains function long before substance use begins, according to a new study ...