LOS ANGELES — Using low-dose tissue plasminogen activator (tPA; alteplase) delivered by surgical catheter to remove clots of pooled blood from the brain's ventricles after intraventricular hemorrhage ...

The clot-dissolving medication, alteplase, improved stroke patients' recovery by more than 50% when given up to 24 hours ...

For people with ischemic stroke, treatment with the clot-busting drug tenecteplase is associated with a slightly higher likelihood of an excellent recovery and reduced disability three months later ...

Greater thrombus permeability, a more distal thrombus location, and longer time to assessment are factors associated with outcomes of recanalization of an arterial occlusion in patients with acute ...

A major international analysis of 2,313 patients, median age 71, found that giving an IV clot-busting drug before mechanical clot removal modestly increases brain-bleeding risk compared with ...

In a randomized clinical trial, giving the clot-busting medication alteplase up to 24 hours after stroke symptoms first appeared increased the odds of better recovery by 50% compared to those who ...