President Donald Trump on Sunday issued a stark warning to Iran against retaliating on U.S. targets in the Middle East while also predicting Israel and Iran would “soon” make a deal to end their escalating conflict.

The conflict, the most intense fighting between the two countries in decades, has been met in the United States with feelings of “frustration and helplessness,” as well as heartbreak.

Explosions have been seen over Tel Aviv and Jerusalem as the country faces yet another barrage of missiles from Iran. It comes after explosions were reported in central Tehran, as attacks continue between Iran and Israel.

Israel had a plan to assassinate Iranian Supreme Leader Ayatollah Ali Khamenei, but President Trump vetoed the operation, according to reports.

Israel launched an expanded assault on Iran on Sunday, targeting its energy industry and Defense Ministry headquarters, while Tehran unleashed a deadly barrage of missiles.