Research led by the Max Planck Institute for Biology of Aging in Cologne reports that misincorporation of ribonucleotides into mitochondrial DNA (mtDNA) initiates an inflammatory cascade.

Chronic kidney disease (CKD) affects more than 700 million people worldwide and is caused by genetic and environmental ...

There's a molecule that our body makes from vitamin B5 that is critical for all of the metabolic processes essential for human life. And when something goes wrong in that molecule's production, it ...

Mitochondrial dysfunctions are associated with a variety of pathologies, and the onset and progression of disease are accompanied by alterations in extracellular biochemical and mechanical signals.

Essential cofactor coenzyme A is derived from vitamin B5 and is critical for all metabolic processes essential for human life ...

Nearly every cell in your body depends on mitochondria to survive and function properly. Mitochondria provide 90% of our ...

Many of us remember from high school biology class that mitochondria are the cell’s “power plants.” These small kidney-bean-shaped structures are what convert nutrients from food into ATP — the cell’s ...

Researchers at Leiden University in the Netherlands developed kidney organoids derived from patient stem cells to examine the ...

In 2016, sarcopenia was recognized as a disease and given an ICD-10-CM code (M62.84). 3,4 However, the originating causes of sarcopenia are largely unknown and have no clinical treatments at present, ...

The evidence is amassing that alterations in brain energy metabolism are the first cause of all psychiatric disorders, from anxiety to schizophrenia, autism to Alzheimer’s disease. The metabolic ...