The 84-year-old has not been seen or heard from since Saturday night.

The FBI has been briefed on the disappearance of “Today” show host Savannah Guthrie’s mom in Arizona — as cops revealed the missing 84-year-old has physical ailments that limit her ability to move. Authorities have been searching for Nancy Guthrie ever since she was reported missing in Tucson by her family over the weekend.

Chris Cuomo opens his show discussing the latest developments in the disappearance of “Today” host Savannah Guthrie's 84-year-old mother, Nancy.

Dateline: Secrets Uncovered Season 16 explores the chilling case of Dwayne Demkiw, from his mysterious disappearance to an international manhunt and murder conviction.

Mystery surrounds the disappearance of Nancy Guthrie, the mother of US TV host Savannah Guthrie.

Bill Hodge continues searching for answers about his brother Michael, who vanished in March 2004 near west 172nd and Puritas.

PRINCE FREDERICK, MD – A 16-year-old girl disappeared in southern Maryland just before the weekend, launching an urgent search across Calvert County as investigators race to locate her.

"Dateline" is airing a special episode about Jay Lee. Here's everything you need to know to watch, live or later on, if you missed it.