Four years after its discovery, the weight-controlling protein hormone leptin is still making news. At the American Diabetes Association meeting in Chicago June 14, researchers from Amgen Inc. of ...

Obesity has become a global epidemic affecting diverse populations and leading to metabolic syndrome across different sexes and age groups. A significant aspect of obesity is the development of leptin ...

A team of scientists has uncovered a critical mechanism that could pave the way for safer and more effective obesity ...

A research group has identified the so-called PNOC/NPY nerve cells in the brains of mice. When activated, these cells increase food intake and lead to obesity. Interestingly, these nerve cells are ...

Estrogen regulates the brain's energy metabolism in the same way as the hormone leptin, leading the way to a viable approach to tackling obesity in people resistant to leptin, researchers at Yale ...

Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category. Though a complex interplay of genes, diet, and environment contribute, 90% of ...

A brain circuit involving leptin allows mice to carry out vital behaviors, such as eating and sleeping, during anxious episodes. A study led by researchers at the University of Cologne and University ...

Leptins belong to a class of adipocyte-originating hormones that have a variety of functions in the regulation of appetite and metabolism, as well as in immune regulation. The lungs are a rich source ...