Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows study. Rather, the formation of protein into liquid droplets ...

The prion protein forms functional condensates that are enriched at cell-cell interfaces. However, long exposure to copper ions/hydrogen peroxide that result in oxidative stress, triggers a ...

A collection of Articles with associated content and a Q&A describes a selection of factors that influence biomolecular phase separation. They explore advances in methodologies for studying this ...

Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows study. Rather, the formation of protein into liquid droplets ...

Chemidroplet is a chemical tool, that fused the BTB-containing domain to the multivalent DNA binding domain (DBD) and intrinsically disordered regions (IDRs) to readily control the LLPS of these ...

Researchers have identified a new physicochemical principle governing liquid–liquid phase separation in polymer solutions. Their research demonstrates that during the separation of a polymer mixture ...

Crystallization is a well-explored natural phenomenon where atoms or molecules arrange themselves into highly organized solid forms called crystals. This phenomenon has been widely utilized across ...

Genetic engineers can design and assemble sophisticated gene circuits to program cells with new functions, but important signaling molecules can become diluted as these cells grow and divide, causing ...

Liquid-liquid phase separation (LLPS) is a peculiar phenomenon that occurs during crystallization. In a new study, a group of researchers from Doshisha University, Japan, have investigated the ...