DNA replication initiates from precise sites along the genome that are called replication origins. Prokaryotes and viruses generally replicate from a single origin, whereas, because of its complexity, ...
Figure 1: The DBF4 promoter locus contains a strong ori. Figure 2: Replication initiation at the DBF4 locus is largely confined to around 7 h after mitosis or 1 h after G1/S. Precise replication ...
A collaboration of researchers from Harvard Medical School and the University of Virginia, led by Dr. Anindya Dutta, has created an artificial mammalian origin of replication that will facilitate the ...
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