Genetically speaking, it’s a bacterium’s worst-case scenario: during transcription, newly minted RNA sticks to its DNA template, forming a 3-stranded structure known as an R-loop. While these ...
R-loops are structures that form when a strand of RNA (red) forms a stable structure with double-stranded DNA, causing one strand of the DNA to form a loop. R-loops are associated with gene ...
A new study by researchers at the German Center for Infection Research (DZIF) and Heidelberg University Hospital has identified RNA:DNA hybrids, known as R-loops, as structural features that guide the ...
Researchers have figured out how the human body keeps essential genes switched "on" and silences the vast stretches of genetic repeats and "junk" DNA. Researchers at the University of California, ...
A schematic showing how R-loops, a hybrid of RNA and DNA, can form during DNA transcription when the messenger RNA chain being assembled by the RNA polymerase binds to one of the DNA strands. R-loops ...
New research reveals how the RapA enzyme protects against R-loop cytotoxicity in E. coli. Genetically speaking, it's a bacterium's worst-case scenario: during transcription, newly minted RNA sticks to ...
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