Acute myeloid leukemia (AML) impairs neutrophil maturation in bone marrow, with mature neutrophils decreasing by over 78% in marrow and 89% in blood. AML-exposed neutrophils acquire inflammatory ...

Emergency hemopoiesis may maintain blood counts and a proinflammatory environment in MDS, AML, and ICUS. Altered neutrophil subset distributions in MDS and AML show diagnostic sensitivity, with ...

An international research collaboration mapped the glycosylation of proteins from both maturing and mature neutrophils, a type of white blood cell that responds to tissue injury and infection. Their ...

Neutrophils cause time-of-day–dependent collateral tissue damage after sterile injury through an intrinsic circadian program.

Immunotherapy has revolutionized cancer care by training the immune system to detect and destroy tumors. For many patients, ...

Two proteins ensure that cells can take up iron when needed. If both control proteins are switched off in mice, the animals develop severe anemia, as expected. At the same time, surprisingly, a cell ...

In a recent study published in PNAS, researchers elucidated immunologic and genetic perturbations in long coronavirus disease (COVID) patients with pulmonary fibrosis. In the present study, ...

Results open the door to therapies based on chronobiology, the branch of biology that studies how living organisms structure their physiological processes in time.