ascopubs.org

Comparison of clinicopathological features in early-onset breast cancer patients with and without pathogenic genetic mutation.

A predictive model for survival outcome of patients with early-stage medullary breast carcinoma: A population-based study. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This ...
ascopubs.org

Comparison and performance of three plasma next-generation sequencing assays versus tissue testing for the detection of actionable driver mutations in advanced non-squamous non ...

Comparative genomic landscape of patients with lung cancer with high-load versus low-load Epstein-Barr virus infection. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This ...
eLife

Impacts of mutation accumulation and order on tumor initiation revealed by engineered murine colorectal cancer organoids

This study presents a valuable finding on the mutational order for common alterations in colorectal cancer. The evidence of in vitro growth assays comparing mutations is solid, although inclusion of ...
News Medical

How Do Genetic Mutations Cause Disease?

Genetic disorders can occur due to mutations in one gene (monogenic), multiple genes (multifactorial inheritance), and mutation in one or more chromosomes. Point mutations are where one nucleotide in ...
Phys.org

Mutations driving evolution are informed by the genome, not random, study suggests

A study published in the Proceedings of the National Academy of Sciences by scientists from Israel and Ghana shows that an evolutionarily significant mutation in the human APOL1 gene arises not ...