Scientists have created a 6-legged mouse embryo with an extra pair of hindlimbs at the expense of their external genitalia. But far from creating a monster, this rudimentary rodent provides important ...
Image of mouse embryos at the 2-cell stage visualised by light microscopy. Two blastomeres (cells) can be seen inside the zona pellucida (a “shell-like” protective outer layer) of each embryo. Credit: ...
Study reveals that genomic nuclear speckle-associated domains (SPADs) are step-wise organized during mouse early embryogenesis, with key factors contribution in this process. Following mammalian ...
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Role of LADs and Epigenetic Pathways in Nuclear Architecture During Early Mouse Embryo Development
A recent study published in Cell investigates how lamina-associated domains (LADs) contribute to nuclear genome organization in early-stage mouse embryos. Focusing on the zygote and two-cell stages, ...
Mouse embryos can make it to an early stage of development in space. In an experiment conducted in 2021, a few hundred frozen two-cell embryos from mice thawed and grew over four days on the ...
A new study from the MRC Laboratory of Medical Sciences (LMS) in London, UK reveals how ancient viral DNA once written off as "junk" plays a crucial role in the earliest moments of life. The research, ...
A recent Nature study evaluates post-implantation development in humans using embryo-like models based on genetically unmodified human naïve embryonic stem cells (ESCs). Study: Complete human day 14 ...
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