A recent study published in Cell investigates how lamina-associated domains (LADs) contribute to nuclear genome organization in early-stage mouse embryos. Focusing on the zygote and two-cell stages, ...

Image of mouse embryos at the 2-cell stage visualised by light microscopy. Two blastomeres (cells) can be seen inside the zona pellucida (a “shell-like” protective outer layer) of each embryo. Credit: ...

Researchers have discovered a key transition in early embryonic development is facilitated by decreasing levels of a viral protein inserted into the DNA of our early animal ancestors. Researchers at ...

Study reveals that genomic nuclear speckle-associated domains (SPADs) are step-wise organized during mouse early embryogenesis, with key factors contribution in this process. Following mammalian ...

Disrupting maternal gut-immune axis perturbed immune networks in developing mouse brains, revealing potential mechanisms underlying neurodevelopmental disorders.

A new study from the MRC Laboratory of Medical Sciences (LMS) in London, UK reveals how ancient viral DNA once written off as "junk" plays a crucial role in the earliest moments of life. The research, ...

A recent Nature study evaluates post-implantation development in humans using embryo-like models based on genetically unmodified human naïve embryonic stem cells (ESCs). Study: Complete human day 14 ...