Ensemble map of protein structure. The team’s approach integrates different NMR data to create a map of how different parts of a molecular structure move. Tokyo, Japan – Researchers from Tokyo ...
Malathy Palayam, Aleczander Young, Lior Tal, and Nitzan Shabek at the UC Davis Department of Plant Biology are exploring the mechanism by which the plant hormone strigoractone regulates a massive ...
In a new study, researchers have discovered how an enzyme that plays a key role in cancer development functions. The researchers hope the new knowledge will lead to the design of more precise drugs.
University of Delaware biochemist Jeff Mugridge is trying to figure out how so-called mRNA eraser enzymes work in our cells, why those erasers can sometimes misbehave and lead to cancer, and how ...
Synthetic biology is a growing field of research that is aiming to create a new kind of organism. Engineering synthetic proteins that can perform simple cellular functions as they would in real life ...
UTA biochemists are mapping the function of specific enzymes which may facilitate development of new drugs to fight bacterial infection, cancer and potentially neurodegenerative diseases like autism, ...
Doctors have long treated heart attacks, improved asthma symptoms, and cured impotence by increasing levels of a single molecule in the body: nitric oxide. The tiny molecule can change how proteins ...
Cytochrome P450 enzymes constitute a superfamily of haem-containing proteins that catalyse the oxidation of a wide range of exogenous and endogenous compounds. Their function is fundamental to the ...
Nature article shows exactly how calpastatin regulates calpain. Scientists at St. Jude Children’s Research Hospital used a combination of x-ray crystallography and nuclear magnetic resonance (NMR) ...
All life on Earth is unified by its use of a shared set of component chemical compounds and reactions, providing a detailed model for universal biochemistry. However, this notion of universality is ...
Annotations of enzyme function provide critical starting points for generating and testing biological hypotheses, but the quality of functional annotations is hindered by uncertain assignments for ...
Researchers at Baylor College of Medicine and collaborating institutions report in the journal Nature Communications how a mutation in the enzyme SKD3 can cause a form of a genetic disease known as ...
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