Does the shared epitope—a common five-amino-acid sequence in the β1 subunit of the HLA-DR molecule—act as a ligand to trigger innate immune signalling? This hypothesis, put forth by Joseph Holoshitz ...
Basic Tool Has Copious Uses in Development of Vaccines and Protein Therapeutics Epitope mapping, initially a basic-science tool for understanding the 3-D interactions between antigens and antibodies, ...
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