Background: Perivalvular abscess is an ominous development in patients with infective endocarditis. There is little information concerning the long-term outcome of these patients. Methods: Patients ...

CHF: Congestive heart failure; CI: Contraindication; DM: Diabetes mellitus; ICU: Intensive care unit; IE: Infective endocarditis; iv.: Intravenous; LV: Left ventricle ...

Despite advances in antimicrobial therapy, diagnostic imaging and cardiac surgery, infective endocarditis (IE) remains challenging clinically and is associated with high morbidity and mortality.

A 78-year-old man, with aortic valve replacement, presented with deteriorating right vision, pyrexia, and weight loss following dental extraction. Actinobacillus actinomycetemcomitans, a slow growing, ...

Clinical Infectious Diseases publishes clinically relevant articles on the pathogenesis, clinical investigation, medical microbiology, diagnosis, immune mechanisms, and treatment of diseases caused by ...

Since the valves of the heart do not have a blood supply, they are less equipped to fight bacteria than other parts of the heart. Bacteria in the blood passes through the heart and can settle in a ...

Endocarditis is an infection of the heart that can be fatal if left untreated. In this condition, the inner lining of the heart or endocardium becomes infected, usually by bacteria that enter the ...

This is the second most common indication for surgery [8] and encompasses persistent bacteremia, extension of perivalvular infection and resistant organisms. An important distinction is the patient ...