One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

Sarah J. Aitken is at the Center of Molecular and Cellular Oncology, Yale Cancer Center, New Haven, Connecticut 06511, USA, and in the Department of Pathology, Yale School of Medicine, New Haven. Read ...

For decades, biology textbooks taught that DNA’s story could be told with a single image: two elegant strands twisting in a ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

In a quiet lab at Utrecht University, researchers have built a tool that lets you watch one of life’s most serious crises unfold in real time. Inside every cell, DNA breaks, repairs, and sometimes ...

Deep in coastal mangroves and even inside our own mouths, biologists are finding that DNA does not always sit in a simple loop at the cell’s center. A giant microbe called Thiovulum imperiosus has now ...

The herpesvirus can manipulate our DNA with far more precision than previously thought. The virus condenses and changes the shape of our genetic material to hijack the host genes needed for ...

Cancer research, drug safety testing and aging biology may all gain a major boost from a new fluorescent sensor developed at Utrecht University. This new tool allows scientists to watch DNA damage and ...

Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...

Standard genetic sequencing approaches can tell you a lot about the genetic makeup and activity in a sample, like a piece of tissue or drop of blood. But they don’t tell you where specific genetic ...