Editor’s Note: This is part of a new series called Inside the Lab, which gives audiences a first-hand look at the research laboratories at the University of Chicago and the scholars who are tackling ...

The new findings strengthen the "RNA world" hypothesis that describes how the first life on Earth could have used RNA instead ...

RNA is one of the bodies most vital molecules, and it comes in a few forms. For example, messenger RNA fills an essential role in gene expression by copying the sequences of active genes, which are ...

Cedars-Sinai scientists have created a new experimental drug called TY1 that helps the body repair damaged DNA and restore injured tissue. The discovery came from studying tiny molecular messages ...

Treating acute myeloid leukemia (AML) depends on knowing what goes wrong inside cells. A new study suggests that two genetic ...

Transcription factors (TFs) are proteins that regulate the gene expression programs and the identity of each cell by encountering numerous binding partners in the nucleus to turn transcription on or ...

DNA and RNA methylation, initially thought to operate as distinct pathways, have been shown to interact closely, shifting our understanding of gene regulation. A team of researchers from the ...

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...

The human body has to protect itself from pathogens and infectious agents, and there are a variety of ways for the immune system to sense foreign invaders, and react to the threats they may pose. But ...

This image illustrates the chemical structure of a purine molecule, highlighting the numbering of the carbon and nitrogen atoms. The purine structure consists of a pyrimidine ring (positions 1 to 6) ...

Research into how a father’s choices — such as diet, exercise, stress, nicotine use — may transfer traits to his children has become impossible to ignore.