Acute myelocytic leukemia (AML) is a clonal disease of hematopoietic progenitor cells characterized by failure of differentiation and uncontrolled proliferation. Although currently available therapies ...
Exploiting protein homeostasis is a new therapeutic approach in cancer. Nelfinavir (NFV) is an HIV protease inhibitor that induces endoplasmic reticulum (ER) stress in cancer cells. Under conditions ...