One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...
For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new study has shown how ...
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How chromosomes shape up for cell division: Scientists reveal DNA loop formation mechanisms
Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA—its genome—and segregate it equally ...
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How cancer cells tolerate missing chromosomes
A hallmark of cancerous cells is an abnormal number of chromosomes or chromosome arms, known as aneuploidy. While aneuploidy is detrimental to regular cells, it occurs in as many as 90% of tumors. How ...
The human genetic blueprint is deceptively simple. Our genes are tightly wound into 46 X-shaped structures called chromosomes. Crafted by evolution, they carry DNA and replicate when cells divide, ...
Cell division is a precise process, but sometimes it can be impaired, allowing diseases such as cancer to develop. Researchers at Okinawa Institute of Science and Technology (OIST) in collaboration ...
A groundbreaking experiment transforms skin cells into egg-like cells, offering hope for infertility treatments amidst ...
As the cell proceeds through the stages of cell division (from left to right: interphase, prometaphase, metaphase, and anaphase), chromosomes become progressively more compact through a combination of ...
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