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Xijiaqi Formula improves cognition in chronic heart failure rats

In a rat model of chronic heart failure, Xijiaqi Formula improved cardiac indices and rescued learning/memory deficits while ...
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Amyloid β-Peptide Inhibition of the PKA/CREB Pathway and Long-Term Potentiation: Reversibility by Drugs That Enhance cAMP Signaling

Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, No. 20 (Oct. 1, 2002), pp. 13217-13221 (5 pages) Changes in hippocampal function seem critical for cognitive ...
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Evidence Found that CREB Pathway Is More Complex than Previously Thought

Scientists observed that CREB activates specific genes based on the co-factor involved. Investigators at St. Jude Children’s Research Hospital discovered how a transcription factor called CREB ...
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Here we grow: Chondrocytes’ behavior reveals novel targets for bone growth disorders

Histology of growth plate cartilage of achondroplasia model mice in which FGFR3 is overactivated. This study identified SPONDIN1 as a marker for CREB activity. Resting zone was expanded and expressed ...
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Transcriptomic analysis of cAMP/PKA/CREB signaling in invasive lobular breast cancer.

A single center retrospective cohort study of patients with metastatic breast cancer and leptomeningeal disease: Updated survival data and subgroup analyses by breast cancer subtype. Updated safety ...