JACKSONVILLE, Florida — Leg pain and leg cramps aren’t always an orthopedic issue: Both can be signs of peripheral artery disease, or PAD, a serious blood-flow issue with implications for the heart.

DEAR MAYO CLINIC: I'm 52 years old and enjoy long walks with my husband and our dog. I recently started to experience pain in my left calf during our walks. The pain goes away when I rest. Because I ...

Cardiologists reveal the unexpected symptoms of clogged arteries and underlying heart disease that you should know about.

Arterial blockage is one of the most serious threats to cardiovascular health in the United States. Recognizing its early ...

NEW YORK (Reuters Health) - People with poor circulation in their legs benefit from a home-based walking program and are more likely to keep it up over the long term, according to a new U.S. study.

Arteries can become blocked over many decades, before resulting in conditions that can become severe quickly. (Getty Images) Heart problems are very common in the UK, with around 7.6 million people ...

People in their 50s with severely narrowed leg arteries may face a high risk for major amputations despite having emergency surgery to restore blood flow to their legs, new research shows. The ...

DEAR MAYO CLINIC: I'm 52 years old and enjoy long walks with my husband and our dog. I recently started to experience pain in my left calf during our walks. The leg pain goes away when I rest. Because ...