Silent cells deep in your spinal cord may hold a surprising key to healing after devastating injuries and brain disease. A ...

Researchers have uncovered novel aspects of astrocyte function in olfactory, or smell, perception revealing changes in their gene expression patterns that turn these brain cells into a hub of ...

Astrocytes are integral constituents of the central nervous system, serving roles that extend far beyond mere structural support. These specialised glial cells are crucial for maintaining homeostasis, ...

The potential effects of astrocyte dysfunction in neurodegenerative diseases are summarized in Figure 2. AD is characterized clinically by cognitive loss in two or more domains, including memory, ...

When astrocyte function is disrupted, neurons in the brain's motor cortex struggle to execute and refine motion, a new study in mice shows. From steering a car to swinging a tennis racket, we learn to ...

Epilepsy, where patients suffer from unexpected seizures, affects roughly 1% of the population. These seizures often involve repetitive and excessive neuronal firing, with the trigger behind this ...

Yunseon Yang, Jae-Jin Song, Yu Ree Choi, Seong-hoon Kim, Min-Jong Seoka, Noviana Wulansari, Wahyu Handoko Wibowo Darsono, Oh-Chan Kwon, Mi-Yoon Chang, Sang Myun Park, Sang-Hun Lee Proceedings of the ...

The mechanism of astrocytic autophagy plasticity plays a crucial role in AD. When the autophagy-regulating genes (LC3B and SQSTM1) in astrocytes are activated, Aβ is efficiently removed, which is ...

To enjoy the scent of morning coffee and freshly baked cookies or to perceive the warning smell of something burning, the brain needs two types of cells, neurons and astrocytes, to work closely with ...

We will begin by highlighting a subset of the many cellular functions of astrocytes, focusing specifically on those functions that have the most relevance to neurodegeneration (Figure 1). Other ...

From steering a car to swinging a tennis racket, we learn to execute all kinds of skilled movements during our lives. You might think this learning is only implemented by neurons, but a new study by ...